Error while Creating Charm Project

Hi

I am configuring CHARM Sol 7.1 SP11.

TMS landscape is as follows

DEV100-->QAS200-->PRD300 (QAS & PRD as Virtual systems). we have created virtual systems and flagged as a virtual system in smsy.

I have created the project in SOLAR_PROJECT_ADMIN and assigned the  logical components.

While performing the CHECK under Change Management tab in Check TMS domains "RFC destination Cannot be determined"

Any pointers on how to resolve this?

Regard